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MorrisonRowe is an EVERYday sun protection clothing company based in Calgary, Alberta. MorrisonRowe was founded by long-time friends Cara and Tegan after Cara was diagnosed with multiple basal cell carcinomas. Her dermatologist recommended that she cover up as much as possible and wear sun protective clothing when outside. She found lots of options for the beach or sport specific activities but struggled to find casual, everyday UPF 50+ clothing. She didn’t want to look or feel like she was headed to the beach while she was out for daily activities such as going to the park with her kids, walking the dog, or sitting on a patio with friends. Cara and Tegan could not ignore this HUGE gap in the market and the need for casual everyday UPF 50+ sun protection clothing. What started as a need, turned into a business idea and Cara and Tegan embarked on the journey to launch their own UPF 50+ sun protection clothing brand. Our mission is to make sun protection clothing part of your everyday wardrobe so you can grab something from your closet and know that no matter where the day takes you, sun protection is there. We have combined timeless style and everyday comfort with UPF 50+ protection so you don’t have to choose between looking great, feeling good, and protecting your skin. -Cara and Tegan Prior to starting MorrisonRowe Cara worked as a registered nurse in surgical oncology and Tegan  a professional engineer. Neither had any previous fashion industry experience so it was quite a journey to build the brand from scratch. Cara and Tegan had some guiding principles for the brand; they wanted all of their clothes to be rated UPF 50+, they wanted to be a Canadian brand, and they wanted their clothes to be sustainably sourced and ethically made. In terms of the actual clothing, Cara and Tegan had specific design concepts and fabric preferences. To them “everyday” means clothes that are timeless, casual and relaxed. Something that you will reach for any and EVERY day. For the fabrics, Cara and Tegan wanted natural fiber fabrics like Tencel™, hemp, and organic cotton because they offer superior breathability, feel great on your skin, and their production is generally more sustainable. This fabric preference is a definite departure from most available UPF 50+ clothing. Finding fabrics proved to be one of the biggest challenges on the journey to launching MorrisonRowe. (Other than the pandemic and raising young children of course). Cara and Tegan searched tirelessly to find sustainable and ethically made, natural and recycled fabrics that were UPF 50+. Most fabric manufacturers Cara and Tegan contacted had minimal or no experience with UPF testing and rating, especially when it came to using natural fiber fabrics. They knew that natural fiber fabrics with UPF 50+ ratings existed but sourcing them proved to be a challenge. They quickly learned that if they wanted to use natural fiber fabrics they would have to send them for testing and rating themselves. Fabrics were chosen based on what Cara and Tegan wanted in terms of how they feel, the composition, the garment design, and sustainability and then sent for basic UPF testing. If the result came back below UPF 50, Cara and Tegan were back to square one. This happened a few times before they found the right fabrics. All MorrisonRowe fabrics are independently third party tested and rated at a lab in Quebec according to industry standards (ASTM D6544 and AATCC 183) to ensure every colour is UPF 50+. MorrisonRowe fabrics are all free of any chemical treatments to make them UPF 50+.  Rather, the natural characteristics of the fibers, the structure of the fabric, and the colour is what makes the fabric UPF 50+. All MorrisonRowe clothes are designed and manufactured in Canada. Cara and Tegan have worked with a local Calgary designer, Ereau Designs, from the beginning. And manufactured solely in Calgary until recently moving manufacturing to Vancouver. They have styles for women, men, and children and are continuing to expand their catalogue. MorrisonRowe has generously offered a special 10% discount to all Save Your Skin Foundation newsletter subscribers. The code will be available in our May newsletter so hurry up and subscribe if you haven’t already!

Facing a melanoma diagnosis can be a daunting experience. Thankfully, there are various treatment options available to combat this disease. These treatments offer the potential for recovery and a return to a fulfilling life. It’s important to be aware that, like any medical treatment, melanoma treatments can come with side effects. In this blog post, we’ll explore the side effects associated with the most common treatment types, providing insights that can empower patients to navigate their melanoma treatment journey with confidence. Immunotherapy Side Effects Immunotherapy is a treatment that harnesses the body’s immune system to fight cancer cells. As with any treatment, side effects can vary from person to person. They also vary depending on the type of immunotherapy drug. The Canadian Cancer Society  lists the following symptoms: The side effects of Interferon alfa-2b or interleukin-2 (cytokines) for melanoma may include: Flu-like symptoms: Patients may experience symptoms such as fever, chills, and body aches, reminiscent of the flu. Fatigue: General tiredness is a common side effect. Loss of appetite: Anorexia, or loss of appetite, may occur. Digestive issues: Side effects like diarrhea and nausea/vomiting can affect some patients. Skin problems: A rash may develop as a side effect. Low blood cell counts: Some patients may experience a decrease in blood cell counts. Depression: High-dose interferon alfa-2b may lead to depression. Swelling: Interleukin-2 can lead to swelling due to fluid retention. The side effects for ipilimumab, nivolumab or pembrolizumab (immune checkpoint inhibitors) may include: Fatigue: Patients may experience increased tiredness. Diarrhea: Digestive issues, including diarrhea, can occur. Skin problems: Some individuals may develop a rash. Headaches: Headaches may be a side effect. Liver problems: Yellowing of the skin and eyes may indicate liver problems. Thyroid problems: Changes in weight, body temperature, heart rate, and blood pressure may result from thyroid issues. Lung problems: Cough and difficulty breathing can be side effects. It’s important to note that side effects can occur at any time during or after immunotherapy. While most side effects are temporary and can be managed, some may persist over the long term. It is crucial for patients to report any side effects to their healthcare team promptly, as they can offer solutions to alleviate these symptoms and ensure a better treatment experience. Targeted Therapy Side Effects Targeted therapy is a treatment that specifically attacks cancer cells while sparing healthy cells. This approach typically results in fewer and less severe side effects than traditional chemotherapy or radiation therapy. According to the Canadian Cancer Society, common side effects of targeted therapy for melanoma may include: Skin problems: Rashes and dryness can affect some patients. Sun sensitivity: Patients may become more sensitive to sunlight. Muscle bone and joint pain: Some individuals may experience pain in these areas. Fatigue: General tiredness can occur. Digestive issues: Nausea, vomiting and diarrhea may be side effects. Fever: Patients may run a fever. Eye problems: Some individuals may experience issues with their eyes. Abnormal liver function: Liver problems may arise. Swelling: Edema may develop. Just like with immunotherapy, side effects from targeted therapy can appear at any time during or after treatment. While many side effects resolve on their own or with medical intervention, it’s crucial for patients to communicate any concerns with their healthcare team. Radiation Therapy Side Effects Radiation therapy is designed to target cancer cells with minimal harm to surrounding healthy tissue, but some damage might still occur, causing side effects during, in the days or weeks after or even years after the treatment. According to the Canadian Cancer Society, the side effects will depend on the size and area being treated, the dose and the treatment schedule. The side effects may include: Skin problems: Redness and irritation of the skin may arise. Fatigue: General tiredness can be a side effect. Hair loss: Hair loss can occur in the treated area. Sore mouth and throat: When radiation is aimed at the head or neck, some patients may experience mouth and throat discomfort. Lymphedema: This swelling condition may occur when radiation targets the underarm or groin area. Similar to other treatments, side effects from radiation therapy can appear at different times. Most of these side effects are manageable, and it’s important for patients to inform their healthcare team of any issues. Surgery Side Effects Surgery is a common treatment for melanoma, but it can also have side effects. According to the Canadian Cancer Society, these side effects may include: Pain: Pain is often managed with pain medicines. Scarring: Surgical procedures can result in scarring. Bruising: Some bruising may occur. Changes to skin color: Skin color changes may develop. Wound infection: Infections at the surgical site can occur. Numbness: Some patients may experience numbness in the treated area. Poor healing: Healing issues can arise. Lymphedema: Lymph node dissection may lead to swelling. As with other treatment methods, side effects from surgery can happen at various times. While most side effects are temporary and can be addressed, open communication with the healthcare team is essential. In conclusion, melanoma treatment is a complex journey, and understanding the potential side effects is a critical part of it. While these side effects can be challenging, most are manageable with the support and guidance of a healthcare team. It is essential for patients to communicate any side effects promptly, as addressing them early can significantly improve the overall treatment experience and ultimately contribute to a better quality of life during and after melanoma treatment.

The Canadian Cancer Society (CCS) released their 2023 statistics document in November, and to ring in the new year we would like to recap some of their findings. While some of these findings are daunting, we still continue to see decreasing mortality rates for melanoma. This demonstrates that access for Canadians to innovative treatments, including clinical trials, means that fewer Canadians are losing their lives to melanoma. Please note that the CCS did their last full review of statistics in 2021. This means that the following statistics have not been updated since then, as melanoma was not included in the 2023 updates. The rate of melanoma skin cancer diagnoses is still increasing although this is a largely preventable cancer (11) Melanoma represented 4.5% of cancers diagnosed in male-identifying people and 3.6% of female-identifying people in 2023 (13) Melanoma was the fourth diagnosed cancer in Canadians aged 30-49 years (15) The largest age-standardized incidence rate increase since 1984 has been melanoma in males, at a steady rate of 2.2% per year (19) Higher incidence rates of incidence and mortality have been observed in coastal provinces, such as British Columbia, Nova Scotia, and Prince Edward Island (22) The lifetime probably of a Canadian developing melanoma is 2.3% (26) In 2023, 1.8% of male-identifying Canadians died of melanoma, as did 1.1% of those who were female-identifying (37) The mortality rate for melanoma continues to decline in Canada, by -2.6% per year in male-identifying people since 2013 and -3% per year in female-identifying people since 2014 (46, 43) Get Support Save Your Skin Foundation wishes to bring hope and support to all those touched by melanoma, non-melanoma skin cancers, or ocular melanoma – whether they are newly diagnosed, currently undergoing treatment, in remission or referred to as “NED” (no evidence of disease). WE INVITE ALL SKIN CANCER PATIENTS, AT ANY STAGE, TO GET IN TOUCH. We are here to help. Call us at 1-800-460-5832 or email info@saveyourskin.ca The information above was sourced from: Canadian Cancer Statistics Advisory Committee in collaboration with the Canadian Cancer Society, Statistics Canada and the Public Health Agency of Canada. Canadian Cancer Statistics 2023. Toronto, ON: Canadian Cancer Society; 2023.

World Cancer Day is on February 4th and is a day to spread awareness of cancer as a whole and to encourage its prevention, detection and treatment. This year, we had the pleasure of speaking with Harjeet Kaur, a stage 4 rare blood cancer survivor who, after her diagnosis, became a wonderful advocate for other cancer patients and caregivers. Her story is one that encompasses the confusion, fear, and ultimately willpower that comes along with a cancer diagnosis. We thank Harjeet for sharing her story with us and giving us insight into her incredible resilience. CAN YOU SHARE A LITTLE BIT ABOUT YOUR PERSONAL JOURNEY WITH CANCER? WHEN WERE YOU DIAGNOSED AND WHAT EMOTIONS DID YOU EXPERIENCE AT THAT MOMENT? Harjeet Kaur: My story has been interesting. I migrated to Canada in 2018 with high hopes of settling down, having a family and having a better career. But life had different plans for me and my world completely flipped upside down in 2019, when I started having high fevers which were ongoing for two and a half months. I went to the doctor but the only answers I really got was that it might be viral or a flu and to take Tylenol every 2 hours to cut down the fever. Along with fevers I started having rigour episodes daily.  I went to the emergency room so many times, and had to wait for 6-8 hours to get answers and those times were really challenging for me. Finally, I was admitted to the University of Alberta hospital where I was treated as a research patient because no one knew what was going on with me. I had a couple of biopsies, surgeries and scans but there were no answers. It took them 3 months to diagnose me, and when I finally figured out what was going on it was August 27th, 2019. At that point I was going to move back to India to get some answers, but the doctor rushed in and told me I had stage four, rare blood cancer. I was 32 at the time and I had no idea that was. The doctor told me that they thought I should stay in Canada because I was stage 4 and had to start treatment right away. Listening to that news, my life completely stopped – I was in shock. My mom and brother were there with me, my husband had gone to see my family doctor to plan my move back to India, but then I called him and told him I had the diagnosis – I couldn’t tell him on the call that I had stage 4. After not having answers for a few months, to hear that I was stage four was really shocking. To get a late diagnosis at age 32 was something I never would have expected – it was a rollercoaster ride. HOW LONG WERE YOU ABLE TO START TREATMENT AFTER YOU WERE FIRST DIAGNOSED? Harjeet Kaur: They did a skin biopsy which finally showed the diagnosis after 3 months. As soon as I got the diagnosis in the afternoon, they wanted to admit me right away and start the treatment as I was losing time. But we asked them for a few hours to process the news. Since it was 3 months delayed, we wanted to connect with our family doctor and the medical team we were talking to in India and update them. So I actually ended up starting chemotherapy the next day. WORLD CANCER DAY IS ABOUT RAISING AWARENESS AND TAKING ACTION. WHAT MESSAGE WOULD YOU LIKE TO CONVEY TO THOSE WHO MAY BE FACING A CANCER DIAGNOSIS FOR THE FIRST TIME? Harjeet Kaur: As we all know, cancer is tough. Not only for the person, but also for the family. Going through the diagnosis, treatment during COVID (35 days of isolation) – all of it is tough. The number one thing I would tell someone who is facing a cancer diagnosis is to not lose hope. There are a lot of support groups and communities out there who can help. You can also ask for help from your friends and family. You don’t have to face this journey alone. Get Support Save Your Skin Foundation wishes to bring hope and support to all those touched by melanoma, non-melanoma skin cancers, or ocular melanoma – whether they are newly diagnosed, currently undergoing treatment, in remission or referred to as “NED” (no evidence of disease). WE INVITE ALL SKIN CANCER PATIENTS, AT ANY STAGE, TO GET IN TOUCH. We are here to help. Call us at 1-800-460-5832 or email info@saveyourskin.ca

RARE DISEASE DAY IS ON FEBRUARY 29TH AND IS A DAY DEDICATED TO RAISING AWARENESS FOR PATIENTS, FAMILIES AND CARERS AROUND THE WORLD THAT ARE AFFECTED BY RARE DISEASES. SEAN WACHTER IS AN INCREDIBLE RARE MELANOMA SURVIVOR FROM THE UNITED STATES WHO HAS USED HIS STORY AND HIS PASSION FOR WRESTLING TO GIVE BACK AND INSPIRE OTHERS. WE THANK SEAN FOR SHARING HIS STORY WITH US. CAN YOU DESCRIBE YOUR JOURNEY WITH STAGE 4 RARE MELANOMA? SEAN WACHTER: The actual receiving my diagnosis was not difficult, it was getting to the point of someone finally giving me a diagnosis that was the difficult part. I spent a period from about March of 2016 to right up until when I got sick on September 26, 2016 visiting various doctors and telling them that something wasn’t working with my body correctly. I had unfortunately been in a really bad accident about three or four years prior where I broke my neck, back and lost my ability to walk, and once I had regained my ability to walk unassisted was when things started feeling off in my body. Every doctor I went to said “It’s from your accident. This is post concussion syndrome” – they wanted to write it off. Around May of 2016, I went on a date and while we were sitting there I got very dizzy and collapsed while eating. I was taken by ambulance to a local medical facility and they said I was just dehydrated and sent me on my way. About a month later, I was at a Mets baseball game and I blacked out right in the middle of the concourse. I wound up going to two separate hospitals that evening, because I wasn’t satisfied with the level of care I was getting at the first one. But the second one said the same thing, that I was dehydrated and had the flu so I was sent home again. About a month later, the same thing happened and I was taken to a hospital in New York City. So now I was starting to deal with good, world renowned hospitals but I still wasn’t taken seriously. In between these bigger incidents I had also gone to my local medical facility about six times telling them “Hey, something’s not right. Please listen to me”. The next time I went back was September 23, 2016 and I was not treated very well. I was basically told “You’re either drunk or hungover” but that was impossible because I didn’t drink. I didn’t know it at the time, but they were actually going to put me on a psychiatric hold – they thought I was making it all up in my head so they were going to hold me overnight for observation. I started to argue with them then, and pushed to see if they could give me an MRI but they refused because they thought nothing was wrong. Essentially, all they were willing to do was give me a bag of fluid so I ended up leaving on my own and going to my parents house because I knew something was wrong but I didn’t know what yet. My parents had to leave for a few hours that weekend and within 10 minutes of them being gone, I was on the floor throwing up, my face was drooping and my legs wouldn’t work. Luckily, I managed to call my Dad and he came back and sprung into action. He took me back to the hospital but they didn’t want to help me again – they just said “Oh he’s back”. I proceeded to throw up all over myself, and they seemed more aggravated than anything because they were asking me to fill out the insurance forms but I couldn’t use my hands properly. I got put into the non-emergency area of the hospital and I asked for a CT scan but the nurse practitioner said I was too young. A few minutes after that, I started having a stroke, which unfortunately my parents had to see. That was when we found out I had a golf ball sized tumor in my cerebellum that caused a massive, massive hemorrhage. A doctor took my Dad aside while I was in surgery and told him I had late stage melanoma. I regained consciousness two days after the surgery, and I remember my dad just rubbing my ankle and telling me the news. And I said to him, “Okay, we’re gonna fight this thing and we’re gonna beat it”. I was in the hospital for about a month and the people around me really showed up. My high school and college football teammates wrote up a spreadsheet of who was going to see me and what they would bring. I went to Sloan Kettering Hospital and I had radiation to clean up the surgical bed. When I was getting cleaned up, I noticed something that really influenced my cancer journey. At the time, they didn’t have a separate pediatric unit for radiation and I looked around and I saw a lot of sick kids that were maybe two or three years old. And I just thought “I’m not gonna sit here and feel sorry for myself. I’ve made every mistake a 31 year old man can make, and these kids haven’t even had a chance to steal a cookie yet”. So at that moment, I decided that whatever happens, happens. I came across an American former football player whose name is Inky Johnson, and he was speaking about how it’s not always about you, it’s about the people who come to lift you up. And I think that sometimes as a cancer patient or cancer survivor, it gets lost on us that while it may seem like we’re in the middle of the ocean surrounded by sharks by ourselves, in actuality there are still people around us, and we have a responsibility to them too. So the “It’s not about you” really resonated with me. I continued to go on with my life, and we tried different immunotherapies and chemotherapies that unfortunately caused my liver to keep crashing. I went to the ICU and was told that I had a rare complication called lepto meningitis disease where the cancer spreads to your spinal cord fluid, and essentially the cells start to coagulate and you lose your brain function. I was told I had 12 weeks to live and to get my affairs in order. That was a right hook that sent me to my knees real quick. But I’m stubborn and didn’t want to accept it. With great research and clinical trials, we were able to find out that I had certain mutations that I could use to my advantage and that pretty much stopped the progression. All of a sudden, I started getting more and more time, which was really amazing. Around April of 2017, my doctor asked if I wanted to try another infusion on top of the two pills I was taking already. And that actually started to send the future scans into regression – I was having one of the best responses you could have to the medication. I decided I wanted to do something more, and I began coaching high school football. It was cool because me being sick really held the kids accountable. If a guy showed up late to practice, you’d have someone on the team saying “He was in chemo today, but you’re late?”. So “What’s your excuse? ” became their rallying cry. It was amazing because at one of the games, my friend arranged for all of the kids to wear these shirts that said Long Beach Football on the front and Coach Wachter Strong with the melanoma ribbon and the saying “What’s your excuse” on the back. It makes me cry to this day. My scans were still regressing at that point and no one could really make sense of it. At that point, my parents talked to me and suggested I get back out there, because I’d fallen apart physically – I used to be in great shape but I lost that. So I put myself out there and started going on dates, and after a few attempts I saw my current wife on Bumble. I recognized her through a mutual friend and we started talking on Facebook. I asked her on a date and we spent 6 hours just talking. When I told my mom about her she actually said that we were born 5 houses apart, so she was the first girl I ever hung out with! Within a few months, we moved in together and I started helping her raise her daughter, which has been the biggest blessing. I have done so many cool things, but raising my stepdaughter has been the coolest thing I’ve gotten to do. She’s my best friend. I have no problem telling people my best friend’s eight year old because it’s her and my wife who made me realize I was not only going to beat cancer, I was going to go through it in a spectacular fashion. I decided to go into business and open an independent coffee chain on Long Island, both to show myself I could and to leave my wife and stepdaughter with something just in case. I always tell people that the coolest thing about doing the coffee shop was that it showed me what I still had in the tank because I would go from six o’clock in the morning to one o’clock in the morning working at our three locations. It’s cool to say I got to run a company from a chemo chair. Sometimes people treat cancer patients like they are totally disabled, so that showed me I was still able and that no matter the circumstances I needed to keep living my life. In the summer of 2021, I got some more scans done and they showed further regression without treatment. So I took my last IV infusion of immunotherapy and got to ring the bell, which was awesome. I was still taking the oral chemo pills, so I wasn’t fully good yet but my scans and spinal taps kept coming out positively so in 2022 the doctors asked if I wanted to stop taking the chemotherapy pills. It was very fitting for me because in March of 2022 my wife, my stepdaughter, and I were going to see a WWE live event in Connecticut. I absolutely love wrestling so I rented a limousine for us and got premium tickets. When we were on the way, my phone rang, and I saw the number of the hospital. I didn’t know if I wanted to answer it right then and there just in case but I begrudgingly picked it up, and I got a “Congratulations. As of right now you are the only documented survival case of this type of cancer”. I was crying happy tears and I got to tell my wife and stepdaughter. It was amazing. My buddies wanted me to throw a party, but I did feel some survivor’s guilt so I decided to throw a fundraiser for Memorial Sloan Kettering Kids. It was a wrestling fundraiser and one of my friends had this brilliant idea of putting a poll on Facebook, essentially saying “If Sean wrestles, will you donate more money?”. I wrestled and it was a big success. Since then, I married my wife and we had our miracle baby. We also hosted another fundraiser where I wrestled in honor of my friend who passed away. It was such a wonderful event, it was twice as big. It was attended by local politicians and the press did an article on me that I put it on my LinkedIn, and from that ESPN found me. From there, I started wrestling a lot more and now we’re working on some amazing stuff. It’s been a crazy ride and I think my story really is a testament to folks that there’s life during and after cancer. I don’t think anyone should let their cancer diagnosis get in the way of them continuing to make their plans and live their lives. Of course that’s easier said than done but something as simple as getting out of the bed in the morning is still a victory over cancer. To me, without cancer there’s no wrestling and I realize that I have this responsibility to keep spreading awareness and sharing my story. I just hope that if somebody hears my story or sees me wrestle, they’re able to live a little bit fuller, or fight a little bit harder. I’d go down the same road 1000 times again, if it helps one person out. To learn more about Sean’s story and get in contact with him, please click the button below.

Melanoma, the most dangerous form of skin cancer, can present unique challenges when it develops on the head or neck, particularly on the scalp. In this blog post, we will look at the distinctive characteristics and considerations for melanoma on the scalp, which are crucial for effective diagnosis, treatment, and follow-up care. Behavior and Treatment Differences When melanoma occurs on the head or neck, it may behave differently than when found on other parts of the body. The complexity of the anatomy in these areas, with numerous blood vessels and lymph nodes, makes it potentially easier for melanoma to spread. As a result, treatment for melanoma on the head, neck, or scalp tends to be more aggressive.[1] Reconstructive Surgery Considerations Reconstructive surgery may be necessary, especially after cancer surgery on the head or neck. This can involve immediate reconstruction or a delayed approach, depending on factors like the stage of cancer and the need for additional surgeries. The waiting period allows for thorough examination and testing to determine the necessity of further procedures. High Prevalence of Melanoma on the Scalp Despite accounting for only 9% of the total body surface, the scalp harbors 20% of melanoma cases. A literature review highlights that scalp melanomas are more common in the elderly and men and have a 10-year survival rate of 60%.[2] Histological Diversity and Diagnosis Scalp melanoma encompasses a heterogeneous group of types, including lentiginous melanoma, desmoplastic melanoma, superficial spreading, and nodular melanoma. All suspicious lesions should be biopsied, with excisional biopsy often recommended.[3] Prioritizing Awareness and Follow-Up Care Given the aggressive nature of melanoma on the scalp, heightened awareness and proactive follow-up care are crucial. Regular check-ups, including thorough cancer examinations and relevant testing, can facilitate early detection. This, in turn, improves the chances of a positive outcome. If you suspect any unusual changes on your scalp or have concerns about melanoma, it’s essential to consult with a dermatologist promptly. Remember, knowledge and awareness are powerful tools in the fight against melanoma, and early intervention can make a significant difference in your overall health and well-being. Get Support Save Your Skin Foundation wishes to bring hope and support to all those touched by melanoma, non-melanoma skin cancers, or ocular melanoma – whether they are newly diagnosed, currently undergoing treatment, in remission or referred to as “NED” (no evidence of disease). WE INVITE ALL SKIN CANCER PATIENTS, AT ANY STAGE, TO GET IN TOUCH. We are here to help. Call us at 1-800-460-5832 or email info@saveyourskin.ca [1] “Treatment May Differ for Melanoma on the Head or Neck.” Www.aad.org, www.aad.org/public/diseases/skin-cancer/types/common/melanoma/head-neck. Accessed 3 Jan. 2024. [2] [3] Licata, Gaetano et al. “Diagnosis and Management of Melanoma of the Scalp: A Review of the Literature.” Clinical, cosmetic and investigational dermatology vol. 14 1435-1447. 7 Oct. 2021, doi:10.2147/CCID.S293115

Melanoma is a type of cancer in which malignant cells form in the melanocytes (the cells that produce melanin or pigment in the skin). Melanoma can occur anywhere on the skin and can metastasize (spread) to other parts of the body. There are several subtypes of melanoma, including cutaneous, acral, mucosal, ocular, and even amelanotic melanoma. Here are some common questions about melanoma: WHAT ARE MELANOCYTES? Melanocytes are a type of cell that produces melanin, the protective black, dark brown, reddish-brown or yellow pigments that colour our skin and hair. The melanocytes are mostly found in the epidermis but can also occur elsewhere, like in the matrix of the hair.[1] WHAT CAUSES MELANOMA SKIN CANCER? Melanoma skin cancer is influenced by various risk factors, with the primary contributor being exposure to ultraviolet radiation (UVR) from the sun and indoor tanning. Having just one blistering sunburn as a child or teenager increases your risk of developing melanoma. Other risk factors include the presence of many moles, atypical moles, congenital melanocytic nevi (birthmarks or moles that are present at birth or develop shortly after), and familial conditions like Familial Atypical Multiple Mole Melanoma (FAMMM) syndrome. Additionally, hereditary factors, such as the CDKN2A gene mutation, Xeroderma Pigmentosum, Werner syndrome, and Retinoblastoma, can elevate the risk. Light-colored skin, eyes, and hair, a personal history of skin cancer, a family history of skin cancer, and a weakened immune system are also identified as significant risk factors.[2] WHAT DOES MELANOMA SKIN CANCER LOOK LIKE? Not all melanomas have the same appearance. Depending on your skin colour, the melanoma might be brown, black, reddish, tan, sometimes even blue! Though most melanomas develop on normal-looking skin, some develop on existing moles. The best way to catch a melanoma early is to look for anything new, changing or unusual on your skin. A common and effective tool to help you spot melanoma is the ABCDEs of Melanoma: A stands for asymmetry, where one half of the lesion does not match the other in shape. B stands for irregular borders; melanomas often have jagged or notched edges instead of smooth contours. C stands for colour; melanomas sometimes have more than one colors within the lesion, such as brown, black, tan, red, blue, or white, in contrast to the more uniform shades seen in benign moles. D stands for diameter, with melanomas tending to be larger than other moles, or grow larger over time. E stands for evolving, highlighting the importance of observing any changes in texture, elevation, size, colour, or the development of symptoms like bleeding or itching. Regular skin self-examinations and professional skin checks are vital for early detection, as prompt medical attention significantly improves the chances of successful melanoma treatment. IS MELANOMA SKIN CANCER DANGEROUS? Melanoma is one of the most serious forms of skin cancer. The Canadian Cancer Society estimates that it caused 1,200 deaths in Canada in 2022. The outlook for individuals with melanoma can vary significantly. Most melanomas can be cured if detected and treated before they have a chance to spread. Early detection and removal of melanoma are essential for a full recovery. HOW IS MELANOMA SKIN CANCER TREATED? There are various treatment options for melanoma. When someone is diagnosed with melanoma, their healthcare team discusses the best melanoma treatments for them and works with them to develop a treatment plan. Here are some of the most common treatment options: Surgery Immunotherapy Targeted Therapy Radiation Therapy Chemotherapy Clinical Trials Get Support Save Your Skin Foundation wishes to bring hope and support to all those touched by melanoma, non-melanoma skin cancers, or ocular melanoma – whether they are newly diagnosed, currently undergoing treatment, in remission or referred to as “NED” (no evidence of disease). WE INVITE ALL SKIN CANCER PATIENTS, AT ANY STAGE, TO GET IN TOUCH. We are here to help. Call us at 1-800-460-5832 or email info@saveyourskin.ca [1] The Editors of Encyclopedia Britannica. “Melanocyte | Biology.” Encyclopædia Britannica, 16 Nov. 2018, www.britannica.com/science/melanocyte. Accessed November 23, 2023. [2] Canadian Cancer Society. “Risk Factors for Melanoma Skin Cancer.” Canadian Cancer Society, cancer.ca/en/cancer-information/cancer-types/skin-melanoma/risks#:~:text=Most%20cases%20of%20melanoma%20skin. Accessed 25 Nov. 2023.

Melanoma on the eye, also known as ocular melanoma, is a rare but serious form of cancer that develops from melanocytes, the cells responsible for producing melanin. This pigment gives color to the eyes, skin, and hair. In this blog post, we’ll delve into the types of ocular melanoma, its diagnosis, and available treatment options. [1] Types of Ocular Melanoma Ocular melanoma includes ocular melanoma, also called uveal melanoma, and conjunctival melanoma. [2] OCULAR/UVEAL MELANOMA The uvea is a three-layered part of the eye. It is made up of the choroid, iris and ciliary body. Uveal melanoma can form in any of these layers and is named for where it forms: Choroidal melanoma begins in the layer of blood vessels – the choroid – beneath the retina. It is the most common type of uveal melanoma. A 2012 article by the American Academy of Ophthalmology discusses the differences between choroidal nevi and choroidal melanoma. Iris melanoma occurs in the front, colored part of the eye. Iris melanomas usually grow slowly and do not typically metastasize, or spread, to other parts of the body outside the eye. Ciliary melanoma originates in the ciliary body, situated in the front of the uvea, responsible for secreting aqueous humor into the eye. These melanomas may grow anteriorly, visible on biomicroscopy as a darkly pigmented mass behind the pupil. Pigmentation can vary. Notably, ciliary melanomas tend to progress more rapidly, with a higher likelihood of metastasizing to the liver, compared to iris melanomas. Treatment for ocular melanoma may involve procedures such as radioactive plaques, proton beam therapy, or even eye removal. Recent advancements, such as the Health Canada approval of Kimmtrak in June 2022, provide hope for patients with unresectable or metastatic uveal melanoma. CONJUNCTIVAL MELANOMA The conjunctiva is the clear tissue that covers the white part of the eye, as well as the inside of the eyelids. Conjunctival melanoma is very rare. It often appears as a raised tumor and may contain little or even no pigment. Conjunctival melanoma most commonly occurs in the bulbar conjunctiva – the mucous membrane that covers the outer surface of the eyeball. Unlike other forms of ocular melanoma that spread most often to the liver, when conjunctival melanoma spreads, it most often spreads to the lungs. Individuals diagnosed with conjunctival melanoma may undergo resection, cryotherapy, topical chemotherapy, or radiation as part of their treatment plan. Diagnosis and Prognosis Melanoma on the Eye Diagnosing ocular melanoma often involves routine eye exams, where some cases may be asymptomatic. The prognosis varies, with uveal melanoma recurrence occurring in less than 5% of cases after primary treatment. However, approximately 50% of people with uveal melanoma may develop metastases, typically in the liver. [3] Treatment Options Treatment for melanoma on the eye depends on the type, location, and stage of the cancer. The aim is to control the primary tumor and prevent recurrence or metastasis. In advanced cases, a range of treatments, including immunotherapy, molecularly targeted agents, and liver-directed therapies, may be employed. Get Support Save Your Skin Foundation wishes to bring hope and support to all those touched by melanoma, non-melanoma skin cancers, or ocular melanoma – whether they are newly diagnosed, currently undergoing treatment, in remission or referred to as “NED” (no evidence of disease). WE INVITE ALL SKIN CANCER PATIENTS, AT ANY STAGE, TO GET IN TOUCH. We are here to help. Call us at 1-800-460-5832 or email info@saveyourskin.ca [1] “Cancerous Tumours of the Eye.” Canadian Cancer Society, cancer.ca/en/cancer-information/cancer-types/eye/what-is-eye-cancer/cancerous-tumours. Accessed 4 Jan. 2024. [2] “CURE OM – Melanoma Research Foundation.” Melanoma.org, 27 June 2023, melanoma.org/patients-caregivers/cure-om/. Accessed 4 Jan. 2024. [3] “Ocular Melanoma.” AIM at Melanoma Foundation, www.aimatmelanoma.org/melanoma-101/types-of-melanoma/ocular-melanoma/. Accessed 4 Jan. 2024.

Melanoma on the Leg: Understanding Detection and Prognosis Melanoma is a serious form of skin cancer that can occur anywhere on the body. While it often develops in areas exposed to the sun, such as the back, legs, arms, and face, it can also appear in less sun-exposed regions. In this blog post, we will explore the key aspects of melanoma on the leg, including its appearance, detection, and prognosis. Melanoma on the Leg: What You Need to Know Location Matters for Melanoma Development Melanomas most commonly develop in areas that have been exposed to the sun, including the legs. It’s essential to recognize that melanomas can also occur in areas with minimal sun exposure, such as the soles of the feet, palms of the hands, and fingernail beds. These hidden melanomas are more frequently found in people with darker skin. Early Detection is Crucial Early detection of melanoma can significantly increase the chances of successful treatment. It’s important to regularly examine your skin for anything new, changing, or unusual, not only on sun-exposed areas but also on sun-protected regions. For women, it’s worth noting that melanomas frequently appear on the legs, while men tend to develop them on the trunk.[1] However, melanomas can arise anywhere on the skin, even in areas not directly exposed to the sun. Appearance of Melanoma on the Leg Melanoma on the leg may present and behave differently in different people. Characteristics include: Spots, sores, moles, or bumps on the skin that change in shape, size, or color Red or brown colored scaly skin Skin that oozes, bleeds, swells, or may feel painful, itchy, or tender[2] Prognosis and Survival Location plays a crucial role in the prognosis and survival of melanoma patients. According to the Canadian Cancer Society, having melanoma on the arms or legs generally has a better prognosis than having melanoma on the central part of the body, head, or neck.[3] Early Detection and Awareness Are Key for Melanomas on the Leg In conclusion, melanoma can affect any part of the body, including the legs. Early detection and awareness of the appearance of melanomas on the leg are vital for increasing the chances of successful treatment. Regular skin self-exams and understanding the different types and locations of melanoma can make a significant difference in achieving a positive prognosis. Remember to consult with a healthcare professional if you notice any unusual skin changes or have concerns about melanoma. Get Support Save Your Skin Foundation wishes to bring hope and support to all those touched by melanoma, non-melanoma skin cancers, or ocular melanoma – whether they are newly diagnosed, currently undergoing treatment, in remission or referred to as “NED” (no evidence of disease). WE INVITE ALL SKIN CANCER PATIENTS, AT ANY STAGE, TO GET IN TOUCH. We are here to help. Call us at 1-800-460-5832 or email info@saveyourskin.ca

This page explores the various treatment options for melanoma and discusses the latest advancements in the field. Your healthcare team will discuss the best melanoma treatments for you and work with you to develop a treatment plan. Surgery Surgery is the primary treatment for early-stage melanoma. There are several surgical approaches, including: Wide Local Excision: This involves removing the melanoma along with some healthy tissue surrounding it. The extent of the removal depends on the thickness and location of the tumor. Sentinel Lymph Node Biopsy: To determine if cancer has spread to the lymph nodes, a sentinel lymph node biopsy may be performed. If cancer is present, more lymph nodes may need to be removed. Immunotherapy Immunotherapy is a promising approach that harnesses the body’s immune system to fight cancer. Various types of immunotherapy drugs are employed in melanoma treatment, including cytokines like interferon alfa-2b and interleukin-2, which help immune system cells communicate and help control the immune response. Additionally, immune checkpoint inhibitors like Ipilimumab, Nivolumab, and Pembrolizumab are used to block checkpoint proteins that cancer cells use to evade immune attacks. Targeted Therapy Targeted therapy targets molecules within cancer cells, such as proteins, that play a role in promoting cell growth and division. By focusing on these molecules, targeted therapy drugs inhibit the growth and spread of cancer cells while minimizing harm to healthy cells. Approximately half of melanoma skin cancers exhibit mutations in the BRAF gene, which drive uncontrolled cell division. MEK and C-KIT gene mutations are less common. Patients with locoregional or metastatic melanoma are often tested for these mutations, and those testing positive may respond to specific targeted therapy drugs.[2] Radiation Therapy Radiation therapy employs high-energy rays or particles to destroy melanoma cancer cells. It is used for different purposes, including destroying cancer cells, reducing the risk of cancer recurrence after surgery, and providing relief from pain or symptoms in metastatic cases. External beam radiation therapy, delivered by a machine, is the primary method for treating melanoma skin cancer.[3] Chemotherapy Traditional chemotherapy is not as effective in treating melanoma as some of the newer therapies. However, it may still be considered in certain cases, such as advanced melanoma that doesn’t respond to other treatments. Clinical Trials Participating in clinical trials can provide access to cutting-edge treatments and experimental therapies. Many breakthroughs in melanoma treatment have come from clinical trials. Get Support Save Your Skin Foundation wishes to bring hope and support to all those touched by melanoma, non-melanoma skin cancers, or ocular melanoma – whether they are newly diagnosed, currently undergoing treatment, in remission or referred to as “NED” (no evidence of disease). WE INVITE ALL SKIN CANCER PATIENTS, AT ANY STAGE, TO GET IN TOUCH. We are here to help. Call us at 1-800-460-5832 or email info@saveyourskin.ca

About The Founder of KRABĒO In November 2021, I was told for the second time that I had cancer. This is not something one gets used to hearing, and at that moment I felt like another bomb went off in my life and my husband’s. This diagnoses was followed by a series of tests that started from the end of November up to the 2021 holiday season. The reason for this was to gain an understanding of this possible recurrence all these years later. Over 17 years ago, I had a beauty mark on my back that itched like a mosquito bite, which I thought was odd. That was back when tanning salons were a trend and I would visit them several times a week to do something about my “milky white” complexion. At this time, I felt I needed those sessions to look more “healthy”. I even had a membership at a local tanning salon! One day, just before settling in for a session, I discussed my beauty mark with the owner who urged me to get it checked out, which I did a few weeks later. I was 24 when it first happened and honestly, I felt I was above it until a lymph node surfaced in September 2021. It was then that I noticed a small lump in my right groin that many doctors thought was harmless, but I had a feeling that it was not benign. I had to persist with the healthcare system to go further and do more tests in order to find out what was wrong. When you have a feeling that something is wrong, you need to advocate for yourself & ask questions. In my case, I was indeed wrong. The doctors discovered after an ultrasound that it was melanoma. This was quite a shock & a return to square one. I hesitated to tell my story when all of this happened, even to my kids, but I would come to understand the importance of sharing one’s life experiences. No matter if it’s good or bad because doing so can help others. My story may be your story too! It made me realize the great lack of resources and knowledge about this disease and how to adequately protect myself from the sun. It’s because of what I went through that I decided to help the people around me and the population by developing a line of UV-protective beachwear. Our beachwear is certified and recognized by the highest world standards of sun protection and it covers 98% of UVA and UVB rays. KRABĒO was born from this desire and is made entirely made in Quebec with love. Now, whenever I see my clothing worn by people from all walks of life, including children, my heart swells at the idea that I was able to do my part in the fight against this preventable cancer that has cases increasing with each passing year. In creating KRABĒO, I find myself with peace of mind. Peace of mind for myself, my family and for you. About KRABĒO At KRABĒO, we believe that the sun, the water and the beach are together a source of well-being. To take full advantage of it all, one thing is essential: sun protection. We love to enjoy the sun. The benefits it brings to our lives are of course impossible to ignore. We tend, however, to forget the risks related to UV rays. We can’t say it enough: ultraviolet rays from the sun lead to premature ageing, the appearance of skin blemishes, as well as skin cancer, which represents a full third of the most widespread cancers in the world.For us, skin protection in all of its aspects lies at the very centre of every one of our decisions; indeed, it is our guiding principle. Our laboratory-tested fabrics are certified UPF 50+ and block 98% of UVA and UVB rays, without any toxic products involved, neither for the skin nor for the planet. They have been carefully chosen to meet two criteria: protecting our skin and preserving the oceans.

Dr. Michael Smylie was the recipient of the 2023 Canadian Melanoma Conference Legacy Award which was presented on February 26, 2023. Kathy Barnard, Save Your Skin Foundation’s founder and former patient of Dr. Smylie, had the honour of saying a few words about this incredible doctor, friend, athlete and father. She read several testimonials from former patients and caregivers, including the following one from her very own sister, Rosemary Westie: “To Mike, When you love someone who’s diagnosed with cancer, the world as you know it comes to an end. When my big sister and best friend was diagnosed I was petrified. I couldn’t imagine a life without her in it, none of our family could. But sadly, as a family, you can only do so much. You can provide love, support, and hope, but at the end of the day, you’re still petrified, because love, support and hope can’t cure this relentless disease. In the early years through the various treatments and surgeries my sister had, we always feared we were on borrowed time. Although she stayed strong and dealt with everything this disease threw at her, there came the day we dreaded, where we were told there was nothing they could do. The panic and fear that set in at that stage was indescribable, I simply could not breathe. But then, when we were at our most desperate, we were granted a miracle.  And that miracle was you, Mike Smylie. I know now, years later, that you are simply a lovely and humble man. You’re a wonderful dad and a friend to many. You are a tremendous athlete, and a connoisseur of excellent rum. In fact, as far as I’m concerned, your only flaw is that you are an Edmonton Oilers fan🤣. But can I tell you, Mike, that when we first met under such dire circumstances, to me, my sister and our entire family, you were this divine, all-powerful, god like, super being, that had my sisters life in your hands. I wonder if you realized that you controlled the fate of our family. Our future, our happiness, whether she would live or die. I think about that now, and what a huge burden that was to place on your shoulders, and to think that you didn’t just carry that burden for her, but for every single one of your patients. I hope we weren’t asking too much of you Mike, but we needed you, desperately. You brought calm to our panic, you brought hope when we felt hopeless. You helped us understand what was happening, and what to expect throughout the treatment, which was invaluable when we were in the eye of the storm.  You always made us feel like she was your only patient and your biggest priority, and we know you did the same for everyone single one of your patients. 🙂 You, my dear, just have to accept that you will always be our super hero. Not the one wearing the cape, but the one wearing the wings, and of course the tight bike shorts. 🤣Thank you Mike, for saving my sisters life. Kath’s sister Rose” Dr. Michael Smylie has been a good friend of the Foundation since its creation. He sits on our Medical Advisory Committee and has been a frequent presenter on our webinars, including our most recent Post-CMC 2023 Update webinar. Dr. Michael Smylie is a medical oncologist at the Cross Cancer Institute, and professor at the Department of Oncology at the University of Alberta in Edmonton. Congratulations Dr. Smylie! Get Support Save Your Skin Foundation wishes to bring hope and support to all those touched by melanoma, non-melanoma skin cancers, or ocular melanoma – whether they are newly diagnosed, currently undergoing treatment, in remission or referred to as “NED” (no evidence of disease). WE INVITE ALL SKIN CANCER PATIENTS, AT ANY STAGE, TO GET IN TOUCH. We are here to help. Call us at 1-800-460-5832 or email info@saveyourskin.ca